2008b-393 2011b-667 2011c-006 administration adverseeffects aids(disease) alliedhealthservices animaldiseasemodels animalmodels animalmodelsinresearch anti-bacterialagents antineoplasticagents arzneimittelentwicklung bayestheorem biochemicalmarkers biochemistry biologicalassay biologicalfactors biologicalmodels biologicalproducts biologicalsciencedisciplines biologicalsciences biomarkers biomathematik biomedicalresearch biotechnology blood-brainbarrier by-products capitalproductivity casestudies catalysis cellbiology centralnervoussystem centralnervoussystemdiseases chemical chemicalmodels chemicalsanddrugs chemicalsynthesis chemistry chemotherapy chimiebioorganique chimiepharmaceutique chineseherbal chinesetraditional clinicalbiochemistry clinicallaboratorytechniques clinicalmedicine clinicalpharmacology clinicaltrials clinicaltrialsastopic computationalbiology computationalchemistry computer-aideddesign computersimulation conception congresses consumereducation contractingout datainterpretation design developmentalpharmacology diagnosis diagnosticandtherapeutictechniquesandequipmentanalytical diagnostictechniquesandprocedures disciplinesandoccupations diseases drug drug-relatedsideeffectsandadversereactions drugandnarcoticcontrol drugapproval drugdesign drugdiscovery drugeffects drugevaluation drugguides drugindustry druginteractions drugresistanceinmicroorganisms drugs drugsdesign drugtherapy drugtoxicity développement economics effectiveness effectofdrugson engineering enzymeinhibitors family farmacokinetica fisheries g-protein-coupled general genetics governmentpolicy healthpolicy healthservicesaccessibility high-throughputscreeningassays history industries internationality investigational investigativetechniques jurisprudence lawandlegislation legislation lifesciences manuals marketing medical medicalresearch medicaltechnology medicinal medicine metabolism methodology methods models molecular molecularbiology molecularmedicine molecularpharmacology montecarlomethod moralandethicalaspects médicaments méthodedemonte-carlo nervoussystem neuropharmacology neuroscience nursing organization peptideantibiotics peptidedrugs personalizedmedicine pharmaceutical pharmaceuticalchemistry pharmaceuticalindustry pharmaceuticalpolicy pharmaceuticalpreparations pharmaceuticaltechnology pharmacocinétique pharmacogenetics pharmacokinetics pharmacologicalbiomarkers pharmacologicalprocesses pharmacology pharmacology/toxicology pharmacovigilance pharmacy phospholipases physiologicaleffect plantpreparations preclinical preclinicaldrugevaluation proteinkinases proteins qu475 qu4c51652007 qualitycontrol qv38p5319372008 qv55 qv736p8872006 qv736s291n2006 qv744 qv745 qv771 qv771i6021991 rarediseases receptors referencestandards research rm315 rna rnainterference rs420 safetymeasures sideeffects simulation simulationmethods simulationparordinateur smallinterferingrna standards statistical statisticalmethods systemsbiology technologicalinnovations technology testing theoreticalmodels therapeuticuse therapies toxicitytesting toxicology transitionelements transitionmetals venom virusdiseases wd308a751a1992 wl141 zoology