2013d-797 antagonists antineoplasticagents bioinorganicchemistry cancer catalysis chemicalsynthesis chemistry chemotherapy congresses design dimethylallyltranstransferase drugdesign drugdevelopment drugdiscovery drugs enzymes genes inhibitors metabolism metalloproteins methods organic organicreactionmechanisms pharmacology proteaseinhibitors proteinase proteins qu135s587o2000 qu141p9272000 qu143 qu143c782e2005 qu143i61e1978 ras structure-activityrelationships testing therapeuticuse trypsininhibitors w3in8691970p