adverseeffects clinicalmedicine complicationsetséquelles diseases drugdeliverysystems drugeffects drugtherapy effetsdesproduitschimiquessurlespoumons environmentalexposure evidence-basedmedicine expositionàl'inhalation fitness general health inhalationexposure internalmedicine lung lungdiseases medical metabolism nanoparticles nanoparticules nanostructuredmaterials pharmacologiepulmonaire physiopathologie poumons pulmonarypharmacology pulmonarytoxicology riskassessment systèmesd'administrationdemédicaments évaluationdurisque