adverseeffects airpollutants clinicalmedicine complicationsetséquelles diseases drugdeliverysystems drugeffects drugtherapy effetsdesproduitschimiquessurlespoumons environmentalexposure evidence-basedmedicine expositionàl'inhalation fitness general health healthaspects healthyvolunteers inhalationexposure internalmedicine lung lungdiseases medical metabolism nanoparticles nanoparticules nanostructuredmaterials nontherapeutichumanexperimentation pharmacologiepulmonaire physiopathologie pollutants poumons pulmonarypharmacology respiratorysystem riskassessment standards systèmesd'administrationdemédicaments toxicity toxicologiepulmonaire évaluationdurisque