adverseeffects clinicalmedicine complicationsetséquelles diseases drugdeliverysystems drugeffects drugtherapy effetsdesproduitschimiquessurlespoumons environmentalexposure evidence-basedmedicine expositionàl'inhalation fitness general health inhalationexposure internalmedicine lung lungdiseases medical metabolism nanoparticles nanoparticules nanostructuredmaterials pharmacologiepulmonaire physiopathologie poumons pulmonarytoxicology respiratoryagents riskassessment systèmesd'administrationdemédicaments toxicologiepulmonaire wf600d7941994 évaluationdurisque