589 analysis antisenseelements(genetics) bacteria bacterialgenetics bacterialproteins biochemicalengineering biochemistry bioconjugates bioengineering biologicaltransport biomedicalengineering biopharmaceutics biosynthesis biotechnologie biotechnology cellmembranepermeability cells chemicalsynthesis chemistry computationalbiology computersimulation conception conjugation cultured derivatives design directedmolecularevolution dna dnaprobes drugcarriers drugdeliverysystems drugdesign drugdiscovery drugs enzymes genelibraries genelibrary genetic geneticengineering geneticintervention genetics genetictechniques genomics glycosylation immobilizedproteins immunoglobulins immunotoxins industrialapplications laboratorymanuals ligands metabolism methods microbialproteins molecularevolution médicaments nanostructures nanotechnology pharmaceuticalbiotechnology pharmacokinetics post-translational post-translationalmodification proteinbinding proteinconformation proteinprocessing proteins proteomics qr151 qu135d5982003 qu25 qu55 qu55a841998 qu55p96624 qu55p966245 qw52p9671986 recombinant recombinantfusionproteins recombinantproteins rm saccharomycescerevisiae science secretion synthesis synthèse technologiedesprotéines therapeuticuse toxins utilization