2011h-354 chromosomes cytology diabetesmellitus geneexpressionprofiling geneticdiseases geneticdisorders geneticpredispositiontodisease genetics genetictechniques human humanchromosomes inborn insulin isletsoflangerhans laboratorymanuals mice non-insulin-dependentdiabetes pancreas physiology qz50 research therapy type2 wk25t9912009