biosynthesis cellculture cells congresses cultured cytology development diabetes diabetesmellitus geneexpressionprofiling geneticengineering genetics growth growthsubstances insulin islandsoflangerhans isletsoflangerhanstransplantation laboratorymanuals mice molecularaspects non-insulin-dependentdiabetes pancreas pancreaticbetacells pathophysiology physiology physiopathology regeneration research secretion susceptibility transplantation type2 wi802e561991 wk25t9912009 wk800i8182010 wk801p1881976