aspectéconomique brain buprenorphine capitalism conditionssociales diseases drugabuse drugaddicts drugoverdose drugs drugusers economicaspects economics educationalstatus espérancedevie governmentpolicy histoire history lifeexpectancy medicationabuse methadonemaintenance médicaments mortalitéprématurée naloxone naltrexone opiatesubstitutiontreatment opioid-relateddisorders opioidabuse opioids poisoning politics prematuredeath prevention publichealth rehabilitation santépublique socialaspects socialconditions socioeconomicfactors suicide surdosage therapeuticuse therapy toxicomanie treatment