2012c-781 2017a-681 aged cardiovasculardiseases cardiovascularsystem complications control diabetes diabetescomplications diabetesmellitus diettherapy diseases epidemiologicfactors functionalfood functionalfoods geneticaspects geneticpredispositiontodisease genetics med060000tec012000med010000 metabolicdiseases olderpeople physiopathology prevention publichealth rc669 rc681 riskfactors statisticsastopic therapy treatment