2013b-317 2013d-455 2015k-684 2017d-594 complications diagnosis diseases drugdeliverysystems etiology gastroesophagealreflux healthriskassessment inhalationexposure lung lungdiseases lungs nanoparticles pathology pathophysiology physiology physiopathology pulmonaryfunctiontests rc711 rc756 respiration respiratoryfunctiontests therapy wf600l666p2013 wf600w518w2017