administration control directlyobservedtherapy drugtherapy economics epidemiology gastosemsaúde globalhealth healthplanning multidrug-resistant nationalhealthprograms organization prevention pulmonary resistênciamicrobianaàsdrogas statistics treatmentoutcome tuberculosepulmonar(epidemiologia;prevençãoecontrole;estatísticasedadosnuméricos) tuberculosis wf300g56272005