alzheimer'sdisease alzheimerdisease autonomicdrugs chemotherapy cholinergic cholinergicmechanisms cholinergicreceptors cholinesteraseinhibitors drugeffects drugtherapy nervegrowthfactor neuroregulators neurotransmitteragents parasympatholytics pharmaceuticalchemistry pharmacodynamics receptors sympatholytics sympathomimetics therapeuticuse wm220c5471991