2013b-224 alcohols aldehydereductase aldosereductase complications diabetes diabetescomplications diabetesmellitus diabetics diabétique enzymes enzymology inhibitors komplikation l-iditol2-dehydrogenase metabolism ouvragesdevulgarisation physiologicaleffect polyols polyolstoffwechsel popularworks primarycare(medicine) primaryhealthcare rehabilitation réadaptation soinsdesantéprimaires sugaralcoholdehydrogenases therapy traitement treatment wk815