agentscardio-vasculaires apoptose apoptosis cancer cardiology cardiovascularagents cardiovasculardiseases chemotherapy chimiotherapie combination cyclicnucleotidephosphodiesterases c¿ur cœur diseases drugtherapy emploienthérapeutique geneesmiddelen hartziekten heart heartdiseases herzkrankheit impotence impuissancesexuelle inhibiteurs inhibitors maladies methods neoplasms nucléotidescycliquesphosphodiestérases pharmacokinetics pharmakotherapie phosphodiesteraseinhibitors qz267c7312005 salvagetherapy therapeuticuse traitement treatment vasculogenic vasodilatoragents wj709o632005