abnormalities adverseeffects analysis carcinogenesis carcinogenicitytesting carcinogens chemicallyinduced congresses cytochromep-450enzymesystem dnarepair drug-induced drugeffects environmental environmentalexposure environmentalhealth environmentallyinduceddiseases evaluationstudiesastopic experimental genes genetics genetictoxicology geneticvariation healthriskassessment medicalgenetics metabolism molecularbiology mutagenicitytesting mutagens mutation neoplasms pharmacogenetics pharmacology qh411s989i1976 qz202g33161983 qz202u5786e salmonella