adrenergicbeta-antagonists adrenergicbetablockers antagonists calcification calcinosis calcium chemotherapy congresses coronarydisease coronaryheartdisease design disorders drugeffects drugs drugtherapy heartdiseases history medical metabolism musclecontraction myocardialcontraction nitrates pharmaceuticalpreparations physiologic physiologicaleffect qv276c142971983 research sociology therapeuticuse wg300m4951992