blood bloodloss bloodtransfusion bonemarrow bonemarrowpurging bonemarrowtransplantation cardiacsurgicalprocedures celltherapy cellulartherapy clinicalmedicine congresses cytotoxicity diseases drugeffects effectofdrugson evidence-basedmedicine fitness general genetictherapy health heart hematopoieticstemcells immunologic internalmedicine medical monoclonalantibodies stemcells surgery surgical therapeuticuse transfusion transplantation treatment wg169b6551991 wh380i6116b1989